Endocrine Abstracts

Introduction: Precocious puberty in boys is the development of secondary sexual characteristics before 9 years of age. Peripheral precocious puberty (PPP), as opposed to central precocious puberty (CPP), is caused by autonomous secretion of androgens or human chorionic gonadotropin (hCG). Testicular volume, penis size, growth velocity, gonadotropin and androgen levels, and bone age readings aid in diagnosing precocious puberty and in identifying its cause. Distinguishing CPP f...

Introduction: Most cases of prepubertal gynecomastia are classified as idiopathic. However, an exogenous or endogenous hyperestrogenism (from estrogen producing testis or adrenal tumors) has always to be excluded. Other rare underlying endocrine causes are congenital adrenal hyperplasia, aromatase excess, hyperthyroidism and hyperprolactinemia1,2.We report a transient hyperprolactinemia, beside other ignored clinical and hormonal signs of estr...

Background: Data concerning pubertal development and testosterone (T) in obese male adolescents (ObA) are scarce and contrasting. Underperforming T immunoassays and poor assessment of pubertal development might explain discordant findings. Although SHBG is markedly affected, few studies report free T (FT) levels.Objective: To study if ObA have conserved FT levels despite low total T (TT) and to investigate if FT is a better indicator of androgen exposure...